Diagnostic Certainty in Registry-Based Estimates of Innate and Intrinsic Immunity Defects
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Abstract
We read with interest the study by Refaat et al describing defects of innate and intrinsic immunity in the Moroccan inborn errors of immunity (IEI) registry [1]. The cohort is particularly valuable because these disorders may remain unrecognized when routine immunological testing is unrevealing. We believe, however, that clarification of diagnostic certainty would strengthen interpretation of the reported frequency and genetic spectrum.
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References
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